A negative implementation is one that excludes a type from implementing a particular trait. Not being able to use a trait is always a safe operation, so negative implementations are always safe and never need to be marked as unsafe.

#![feature(optin_builtin_traits)]

struct Foo;

// unsafe is unnecessary
unsafe impl !Clone for Foo { }

This will compile:

#![feature(optin_builtin_traits)]

struct Foo;

auto trait Enterprise {}

impl !Enterprise for Foo { }

Please note that negative impls are only allowed for auto traits.