Here are some very rough approximate timings of CPython interpreter operations:
f(1) (empty function body): 70-90nsf(n=1) (empty function body): 90-110nso.x: 30-40nso.f(1) (empty method body): 80-160nsCls(1) (initialize attribute in __init__): 290-330nsx + y (integers): 20-35nsa[i] (list) : 20-40ns[i] (also dealloc): 35-55nsa.append(i) (list, average over 5 appends): 70nsd[s] (dict, shared str key): 20nsd[s] = i (dict, shared str key): 40nsisinstance(x, A): 100ns(x, y): 20-35nsx, y = t (tuple expand): 10nsNote that these results are very imprecise due to many factors, but these should give a rough idea of the relative costs of various operations.
Details: CPython 3.6.2, Macbook Pro 15" (Mid 2015), macOS Sierra