diff --git a/ChangeLog b/ChangeLog
index a46c96f..7d15bf0 100644
--- a/ChangeLog
+++ b/ChangeLog
@@ -13,6 +13,11 @@
 ============================
 Release date: TBA
 
+* Catch ``MemoryError`` when inferring f-strings with extremely large format
+  widths (e.g. ``f'{0:11111111111}'``) so that inference yields ``Uninferable``
+  instead of crashing.
+
+  Closes #2762
 
 
 What's New in astroid 4.1.1?
diff --git a/astroid/nodes/node_classes.py b/astroid/nodes/node_classes.py
index 88e62fc..22125b0 100644
--- a/astroid/nodes/node_classes.py
+++ b/astroid/nodes/node_classes.py
@@ -4756,8 +4756,9 @@
                         end_col_offset=self.end_col_offset,
                     )
                     continue
-                except (ValueError, TypeError):
-                    # happens when format_spec.value is invalid
+                except (ValueError, TypeError, MemoryError):
+                    # ValueError/TypeError: invalid format spec
+                    # MemoryError: format spec with huge width (e.g. f'{0:11111111111}')
                     yield util.Uninferable
                     uninferable_already_generated = True
                 continue
diff --git a/tests/test_inference.py b/tests/test_inference.py
index 5f6478a..024ad85 100644
--- a/tests/test_inference.py
+++ b/tests/test_inference.py
@@ -5262,6 +5262,28 @@
         assert value_node.value == result
 
 
+def test_fstring_large_width_no_memory_error() -> None:
+    """MemoryError should not crash inference for f-strings with huge width.
+
+    Regression test for https://github.com/pylint-dev/astroid/issues/2762
+    """
+
+    class OOMInt(int):
+        """An int whose __format__ raises MemoryError, simulating f'{0:>11111111111}'."""
+
+        def __format__(self, spec: str) -> str:
+            raise MemoryError
+
+    node = extract_node("f'{0:>9}'")
+    # Replace the Const value with our OOMInt so format() raises MemoryError
+    # without actually allocating a huge string.
+    fmt_value = node.values[0]
+    fmt_value.value.value = OOMInt(0)
+    inferred = node.inferred()
+    assert len(inferred) == 1
+    assert inferred[0] is util.Uninferable
+
+
 def test_augassign_recursion() -> None:
     """Make sure inference doesn't throw a RecursionError.